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Support of Weight Loss by Altering a Bacterial Population in the GI Tract

详细技术说明

Cornell researchers have identified a bacterial family,Christensenellaceae, found in the intestinal tract and feces andhave established that the absolute orrelative abundance of Christensenellaceae is firstly influenced by hostgenetics and secondly correlated to the phenotypic variance in Body mass Index(BMI).

*Abstract

 

Cornell researchers have showed that Christensenellaceae family issignificantly enriched in lean-BMI subjects (BMI<25) compared to those withan obese-BMI (>30).

 

Potential Applications

• For use as a peripherally acting agent for the anti-obesitymarket
• For use as a probiotic supplement for the nutraceutical market
• For use to identify subject at risk
• For use to monitor method to evaluate the efficacy of an anti-obesity treatment.

 

Advantages

• The invention is using a population of bacteria foundnaturally in the GI tract
• The invention can be an alternative to current methods usingdrugs
• The invention is intended to be simple to produce.

  

== Licensing opportunities available for animal applications ==

 

*Licensing

Jeffrey C. Fearnjcf55@cornell.edu607-254-4502

其他

• PCT publication WO2015164555
• Julia K. Goodrich & al. (2014). Human Genetics Shape the Gut Microbiome. Cell 159, 789–799. doi: 10.1016/j.cell.2014.09.053.

国家/地区

美国