Method for Preparing Structurally Homogeneous Immunoconjugates
- 详细技术说明
- This invention features a method for preparing structurally homogeneous immunoconjugates
- *Abstract
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This invention features a method for preparing structurally homogeneous immunoconjugates. The current procedures to synthesize drug-antibody conjugates usually lead to heterogeneous mixtures in which the number and location of the small molecules vary significantly. This is a problem not only for chemical and biological analysis, but also for FDA approval. Cornell researchers have invented a couple of methods to attach small molecules, including but not limited to agonists, antagonists, cytotoxic drugs and radioisotopes, to monoclonal antibodies. This invention will lead to the generation of drug-antibody conjugates with well-defined ratios.
- *Licensing
- Alice (Xiang) Li, Senior Technology Commercialization and Liaison Officerxl11@cornell.edu607-254-4487
- 其他
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None
- 国家/地区
- 美国
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