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Antimicrobial Peptide for the Treatment of Skin Diseases

详细技术说明

None

*Abstract

Granulysin peptides are small antimicrobial agents with potent activity against bacteria and inflammation. A pharmaceutical composition comprising granulysin peptides as an active agent is administered therapeutically to a patient suffering from a microbial infection.

*IP Issue Date

Dec 2, 2008

*Principal Investigation

Name: Daniel Anderson

Department:

Name: David Eisenberg

Department:

Name: Richard Gallo

Department:

Name: Richard Gallo

Department:

Name: Jenny Kim

Department:

Name: Robert Modlin

Department:

附加资料

Patent Number: US7459439B2
Application Number: US2005304911A
Inventor: Modlin, Robert L. | Kim, Jenny J. | Anderson, Daniel H. | Eisenberg, David S. | Gallo, Richard L.
Priority Date: 12 Sep 2003
Priority Number: US7459439B2
Application Date: 14 Dec 2005
Publication Date: 2 Dec 2008
IPC Current: A61K003800 | C07K001447
US Class: 5140011 | 514012 | 5140024
Assignee Applicant: The Regents of the University of California
Title: Granulysin peptides and methods of use thereof
Usefulness: Granulysin peptides and methods of use thereof
Summary: The granulysin peptide is useful for treating cutaneous microbial infection or inflammation (claimed). It is also useful for treating both early and late stages of inflammatory arthritis, non-infectious inflammatory arthropathy such as rheumatoid arthritis, bursitis, tendonitis, soft tissue injuries, Sjogren's syndrome, systemic lupus erythematous, psoriatic arthritis, gout and other crystalline arthropathies, capsulitis, carpal tunnel syndrome, myositis, polymyalgia, rheumatica, synovitis, Reiter's syndrome, erosive osteoarthritis, autoimmune diseases, inflammation caused by bacterial and viral infection, including response to vaccination, local inflammation in response to trauma, graft rejection, graft versus host disease, and inflammation after tooth extraction or gum disease.
Novelty: New isolated granulysin peptide comprising an alpha-helix turn alpha-helix motif and having amino acid substitution(s), useful for treating cutaneous microbial infection or inflammation

主要类别

生物医学

细分类别

病原

申请号码

7459439

其他

Additional Technologies by these Inventors

• Broad-spectrum Antimicrobial Peptide for the Treatment of Acne and Skin Cancer

Tech ID/UC Case

21723/2004-087-0

Related Cases

2004-087-0

国家/地区

美国