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Mouse Model for Human Non-Alcoholic Steatohepatitis and Steatolic Hepatocellular Carcinoma

技术应用

This model can potentially be very useful in studying NASH and HCC.

详细技术说明

The mouse model described here has been recently developed by researchers at UC San Diego. It mimics the pathology of human NASH and steatolic HCC. NASH appears within 24 weeks and HCC develops within 40 weeks. This model may be used to evaluate compounds, drugs, diet, devices, etc. that prevent or ameliorate NASH and attenuate its progression to HCC.

申请号码

10034462

其他

Related Materials

Nakagawa et al., ER Stress Cooperates with Hypernutrition to Trigger TNF-Dependent Spontaneous HCC Development, Cancer Cell (2014)/j.ccr.2014.07.001

Tech ID/UC Case

24436/2014-361-0

Related Cases

2014-361-0

国家/地区

美国

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