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Optical Detection of Suspended Micro-Objects Using Array Waveguides

详细技术说明

Researchers at UC San Diego have introduced micro fabricated electrodes into fluidic channels to facilitate optical detection by controlling and manipulating the positions, angles, and populations of analytes in micro-fluidic channels, such as cells and DNA, via a dielectrophoretic effect. The researchers have fabricated, using novel technology, microfluidic-photonic-dielectrophoretic integrated circuits with channel waveguides. This represents a new class of circuits particularly attractive to lab-on-a-chip and biomedical applications. [Aspects of this research have been published; see The 17th Annual Meeting IEEE/LEOS, Technical Digest]

*Abstract

Integrated micro-fluidic chips that perform a variety of functions for chemical analysis and biological screening have found wide applications in the pharmaceutical industry and have accelerated the progress of research in biotechnology. Significant efforts have been made to integrate micro-optical and optoelectronic devices with micro-fluidic systems to provide on-chip fluorescence detection and biochemical sensing.

*IP Issue Date

Sep 18, 2012

*Principal Investigation

Name: Chun Hao Randy Chen

Department:

Name: Victor Lien

Department:

Name: Yu-Hwa Lo

Department:

附加资料

Patent Number: US8270781B2
Application Number: US200891414A
Inventor: Lo, Yu-Hwa | Lien, Victor Jie | Chen, Chun Hao Randy
Priority Date: 28 Oct 2005
Priority Number: US8270781B2
Application Date: 28 Oct 2008
Publication Date: 18 Sep 2012
IPC Current: G02B000600
US Class: 385012 | 385004 | 385008 | 385037 | 385129 | 385132 | 42208205 | 42208211 | 435029 | 4352885
Assignee Applicant: The Regents of the University of California
Title: Apparatus and method for improved optical detection of particles in fluid
Usefulness: Apparatus and method for improved optical detection of particles in fluid
Summary: As fluidic-photonic integrated circuit devices useful in flow cytometry system and fluidic-photonic integrated circuit device useful for obtaining information regarding particle (e.g. cells, molecule, DNA segment, virus, analyte and object) suspended in flowing fluid (claimed), for allowing optical detection of particles in fluid, for analyzing white blood cells in AIDS patients, and for performing cancer diagnosis and stem cell sorting.
Novelty: Fluidic-photonic integrated circuit device useful in flow cytometry system comprises fluidic channel, electromagnetic radiation source, and optical guides to receive electromagnetic radiation after radiation has interacted with particle

主要类别

诊断/治疗

细分类别

癌症/肿瘤

申请号码

8270781

其他

State Of Development

This technology is available for licensing.

Tech ID/UC Case

19597/2005-162-0

Related Cases

2005-162-0

国家/地区

美国