Monoclonal Antibody Against Cer164 (Clone 11)
- 技术优势
- Specific antibody to detect Cep164 by antibody-antigen complex formation.
- 技术应用
- Immunocytochemistry/immunofluorescence Immunoprecipitation Western blot
- 详细技术说明
- Centrosomal protein 164kDa (Cep164) is involved in a number of cellular pathways. It is important for microtubule organization and maintenance for the formation of primary cilia. Additionally, Cep164 is critical for G2/M checkpoint and nuclear divisions. Cep164 is also involved in DNA damage-activated ATR/ATM signaling through proper phosphorylation of H2AX, RPA, CHK2, and CHK1. Furthermore, by modulating MDC1, RPA, and CHK1, Cep164 is a mediator that maintains genomic stability critical for chromosomal segregation. The described mouse monoclonal IgG1 antibody binds to human Cep164 and has been described for use in immunocytochemistry/immunofluorescnece, immunoprecipitation, and western blot. The antibodies were derived from GST-Cep164 fusions proteins consisting of amino acids 1-196, 665-873, and 887-1187 of Cep164 and amino acids 1-107 of ATRIP.
- *Abstract
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Mouse monoclonal antibody against the human centrosomal protein 164kDa (Cep164). This antibody binds to the phosphorylation site of Cep164 and has been tested for use in immunocytochemistry/immunofluorescence, immunoprecipitation, and western blot.
- *Principal Investigation
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Name: Yoon Kim
Department:
Name: Eva Y H P Lee
Department:
- 其他
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Related Materials
Additional Technologies by these Inventors
- Monoclonal Antibody Against mtPAP (Clone 3D2)
- Monoclonal Antibodies Against Chk2 (Clone 4B8)
- Monoclonal Antibody Against CEP164 (Clone 13)
- Monoclonal Antibody against ATR-IP (Clone 11)
- Monoclonal Antibody Against Cer164 (Clone 26)
- Monoclonal Antibody Against ATR-IP (Clone 5)
Tech ID/UC Case
25548/2011-387-0
Related Cases
2011-387-0
- 国家/地区
- 美国
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