Device and Method for Controlled Ablation of Microscopic Objects
The method developed by the University of California, Irvine researchers provides a new modality that offers distinct advantages to previous methods. The advantages of the present invention include: fast, patterned linear ablation of microscopic objects, simple operation, high throughput in a uniform manner, and is less expensive. The invention can be used in both research and clinical settings and makes an effective tool available to researchers for the study of molecular mechanisms of biological systems.
Researchers at the University of California, Irvine, have developed a device and method that uses a spatially shaped laser beam for micro-dissection, alteration/ablation, and excitation of living/non-living microscopic objects with high throughput. The purpose of this invention is to develop a device for fast patterned linear ablation of microscopic objects, which is simple to operate and provides high throughput in a uniform manner.
Patent Number: US8571365B2
Application Number: US2009613472A
Inventor: Mohanty, Samarendra K. | Stephens, Jared | Berns, Michael W.
Priority Date: 5 Nov 2008
Priority Number: US8571365B2
Application Date: 5 Nov 2009
Publication Date: 29 Oct 2013
IPC Current: G02B000626 | G02B000642
US Class: 385038 | 385033 | 604020 | 604021 | 606015 | 606016 | 606017
Assignee Applicant: The Regents of the University of California
Title: Apparatus and method for micromanipulation of microscale objects using laser light delivered through a single optical fiber and axicon lens
Usefulness: Apparatus and method for micromanipulation of microscale objects using laser light delivered through a single optical fiber and axicon lens
Summary: Apparatus for micromanipulation of microscale objects using a laser light. Uses include but are not limited to induction of deoxyribonucleic acid (DNA) damage, dissection of neuronal axons, micro-dissection of organelles such as microtubules, thinning of zona pellucida for use in reproductive medicine, and optoporation of exogenous material into cells.
Novelty: Apparatus for e.g. micromanipulation of microscale objects, has axicon lens optically coupled to fiber to form tip to provide spatially shaped elongated laser focused spot for microprocessing and/or microdissection of microscale object
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8571365
Tech ID/UC Case 18710/2008-813-0 Related Cases 2008-813-0
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