Monoclonal Antibodies Specific For The Major Virulence Antigen (v Antigen) Of Yersinia Pestis
- 详细技术说明
- None
- *Abstract
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UC Berkeley scientists have identified several monoclonal antibodies (Mabs) that can be used to detect the V antigen which is one of the essential determinants of virulence in Yersinia pestis, the gram-negative bacterium that caused the bubonic plague. These Mabs may be used to test whether V antigen is present in commercially produced plague vaccine, for epitope mapping of V antigen and determination of V antigen structure as reagents for efficient immunoaffinity purification of V antigen, to screen recombinant hosts expressing cloned V antigen, and as reagents for passive or genetic immunization against Y. pestis in animals or humans.
- *Principal Investigation
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Name: Henry Blank
Department:
Name: Alexander Karu
Department:
- 其他
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Related Technologies
Tech ID/UC Case
18340/1995-001-0
Related Cases
1995-001-0
- 国家/地区
- 美国
