亚洲知识产权资讯网为知识产权业界提供一个一站式网上交易平台，协助业界发掘知识产权贸易商机，并与环球知识产权业界建立联系。无论你是知识产权拥有者正在出售您的知识产权，或是制造商需要购买技术以提高操作效能，又或是知识产权配套服务供应商，你将会从本网站发掘到有用的知识产权贸易资讯。

返回搜索结果

Cell Lines For Fusion Partners For T Cell Hybridomas

*Abstract: These cell lines can be used as fusion partners for generating mouse T cell hybridomas. The antigen specific activation response of the T cell hybridomas generated by these cell lines can be measured using either conventional IL-2 assay or assays for the beta-galactosidase enzymatic activity which is specifically induced in these hybridomas. The ability to measure T cell activation using the beta-galactosidase activity is unique to the hybridomas generated with these fusion partners and allows detection of activated T cells either at a single cell level or in bulk-culture. The beta-galactosidase inducible T cell hybridomas can be used to identify unknown T cell stimulating antigens, receptor ligands, as well as unknown mechanisms of MHC class I and MHC class II antigen processing pathways.
References:
Karttunen and Shastri 1991 PNAS 88:3972-6
Karttunen et al. 1992 PNAS 89:6020-4
Sanderson and Shastri 1994 Int. IMMunol. 6:369-76

欲了解更多信息，请点击这里