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Implantable Analyte Sensor

技术优势: Membrane may be fabricated with precisely defined pore size May be fabricated using standard microfabrication techniquesSensor membrane can be fabricated to give a glucose diffusion test result of at least 1 mg/dl in 330 minutes and an albumin diffusion test result of at most 0.1 g/dl in 420 minutes

*Abstract: Researchers at the University of California have developed an implantable analyte sensor fabricated using an improved porous membrane. A special property of the membrane is a defined pore size, which has a small size distribution (+/- 1%-5%) compared to the size distribution of standard membranes. These membranes can exclude interfering molecules, such as proteins, which could otherwise cause major drift problems for a sensor implanted in vivo.

The membrane of this analyte sensor may be fabricated such that it has a glucose diffusion test of at least 1mg/dl in 330 minutes, and an albumin diffusion test of at most 0.1g/dl in 420 minutes.

*Principal Investigation: Name: TEJAL ASHWIN DESAI
Department:

Name: Mauro Ferrari
Department:

Name: DEREK HANSFORD
Department:

附加资料: Patent Number: US6405066B1
Application Number: US2000528277A
Inventor: Essenpreis, Matthias | Desai, Tejal A. | Ferrari, Mauro | Hansford, Derek J.
Priority Date: 17 Mar 2000
Priority Number: US6405066B1
Application Date: 17 Mar 2000
Publication Date: 11 Jun 2002
IPC Current: G01N0033483 | A61B000500 | A61B0005145 | A61B00051473 | C12M000134 | C12Q000100 | G01N0027327 | G01N002740 | G01N0027416 | G01N003366 | G01N003368
US Class: 600347 | 204415 | 600345 | 600377 | 204403
Assignee Applicant: The Regents of the University of California | Roche Diagnostics Corporationdianapolis
Title: Implantable analyte sensor
Usefulness: Implantable analyte sensor
Summary: Used in vivo , preferably subcutaneously in mammals, e.g. humans, dogs, or mice.
Novelty: Glucose sensor used subcutaneously in mammals, e.g. humans, includes membrane comprising elemental silicon and has specified glucose and albumin diffusion test results

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