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Rapid Nucleic Acid Recognition and Detection of Low Concentrations of Pathogens

详细技术说明
Patent No.: 8,485,025Novel detector for the rapid recognition of low concentration pathogens
*Abstract

  

The present invention provides a standing wave fiber assembly for the collection and detection of a biological target in a complex biological fluid, including: an oscillator; and an elongated fiber coupled to the oscillator, wherein the elongated fiber is selectively exposed to a fluid potentially containing the biological target, and wherein the resonated elongated fiber attracts the biological target, and wherein a change in a response of the resonated elongated fiber indicates the presence of the biological target. The assembly also includes a top cover plate including one or more electrical connections and a port through which the fluid is introduced. The assembly further includes a bottom cover plate including a well in which the fluid is contained. Optionally, the elongated fiber includes one or more probes homogenously functionalized along its length that bind targeted biological materials.

国家/地区
美国

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