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PGS, A Novel Bone Regeneration Scaffold

详细技术说明

None

*Abstract

Large amounts of bone tissue lost to injury or disease are notoriously difficult to replace. Loss of this tissue may result in the amputation of a limb or a serious deformity. Ceramic scaffold materials have been used with limited success. Investigators at the University of Pittsburgh have discovered that the elastomeric polymer Poly(Glycerol Sebacate) (PGS) may be used as a scaffold for bone repair. In vivo data shows that the scaffold was colonized by osteoprogenitor cells and that a critical size long bone defect was bridged in as little as 8 weeks.Application* Bone tissue repairAdvantages* Biocompatible, resorbable, and elastic* Permits mechanical loading of the graft* Pore size conducive to bone healingProvisional Patent Application filed

*Principal Investigation

Name: Charles Sfeir

Department: Dent Med-Oral Biology

Name: Yadong Wang

Department: Bioengineering

国家/地区

美国