Incorporation of double-walled microspheres into polymer nerve guides for the sustained delivery of neurotrophic factors
- 详细技术说明
- None
- *Abstract
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Investigators have developed a biodegradable polymer nerve guide which locally delivers bioactive neurotropic factors in the proper concentration to cross from the proximal to distal nerve stump. Delivery of a neurotropic factor may enhance nerve regeneration and could be used to overcome the current limitations in nerve repair across large defects. This double-walled microsphere delivery system for bioactive Glial Cell Line-Derived Neurotropic Factor (GDNF) has a sustained release profile greater than 50 days in vitro. Provisional Patent Application filed
- *Principal Investigation
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Name: Lauren Kokai
Department: Med-Plastic Surgery
Name: Kacey Marra, Adipose Stem Cell Center Director and Associate Professor
Department: Med-Plastic Surgery
- 国家/地区
- 美国
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