Small Molecure Inhibitors of Dusp6
- 详细技术说明
- None
- *Abstract
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Dusp6 is a protein that limits the expression of fibroblast growth factor (FGF) causing slowed cell division, making it a target for controlling cell growth. Investigators have developed compounds which effectively inhibit Dusp6 and promote the expression of FGF as shown in a zebra fish model.Applications* Treating wounds* Expanding cells* Growing tissues in vitroAdvantages* Novel compound that stimulates cell growthStage of DevelopmentProof of concept in vivo (zebrafish model) with initial hits and follow on compounds.
- *Principal Investigation
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Name: Billy Day, Professor
Department: Pharm-Pharmaceutical Science
Name: Vasily Korotchenko
Department: Pharm-Pharmaceutical Science
Name: Michael Wai Kok Tsang
Department: Med-Developmental Biology
- 国家/地区
- 美国
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