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PROMIS Emotional Distress and Sleep-Wake Function Scales

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*Abstract

BackgroundThe Patient-Reported Outcomes Measurement Information System (PROMIS) is a National Institutes of Health (NIH) Roadmap initiative to develop a computerized system measuring patient-reported outcomes in respondents with a wide range of chronic diseases and demographic characteristics. The PROMIS Network agreed to focus on five domains for cross-site collaboration and item bank development: emotional distress, social functioning, physical functioning, pain, and fatigue. PROMIS was funded by cooperative agreements to a Statistical Coordinating Center (Evanston Northwestern Healthcare, PI: David Cella, PhD, U01AR52177) and six Primary Research Sites (Duke University, PI: Kevin Weinfurt, PhD, U01AR52186; University of North Carolina, PI: Darren DeWalt, MD, MPH, U01AR52181; University of Pittsburgh, PI: Paul A. Pilkonis, PhD, U01AR52155; Stanford University, PI: James Fries, MD, U01AR52158; Stony Brook University, PI: Arthur Stone, PhD, U01AR52170; and University of Washington, PI: Dagmar Amtmann, PhD, U01AR52171). NIH Science Officers on this project are Deborah Ader, Ph.D., Susan Czajkowski, PhD, Lawrence Fine, MD, DrPH, Louis Quatrano, PhD, Bryce Reeve, PhD, William Riley, PhD, and Susana Serrate-Sztein, PhD. See the web site at www.nihpromis.org for additional information on the PROMIS cooperative group and methodology.TechnologyPittsburgh PROMIS is responsible for the development, testing, and validation of the emotional distress banks: two subdomains of internalizing problems (depression and anxiety) and two subdomains of externalizing problems (anger/aggression and alcohol abuse). Pittsburgh PROMIS is also conducting an independent study for the development of sleep and wake function item banks.The development and calibration of the Pittsburgh PROMIS scales for depression, anxiety, anger, sleep disturbance, and wake disturbance were undertaken beginning in March, 2004 and continue to date. The calibration sample included nearly 15,000 individuals (community, psychiatric outpatients, and those with sleep disorders) representative of national census demographics. Based on analyses informed by both classical test theory and item response theory (IRT), expert review, and patient review, final banks of items were calibrated for depression (28 items), anxiety (29), anger (29), sleep disturbance (27), and wake disturbance (16). Unidimensional models could be satisfactorily fit to the constructs. Results indicate that the Pittsburgh PROMIS scales have sound psychometric properties of internal consistency; reliability; construct, content, convergent, and discriminative validity; and independence from gender, age, and education level. More information and precision were provided in the moderate to severe ranges than gold standard measures. Contact OTM for additional information

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美国