Methods and systems for facilitating the diagnosis and treatment of schizophrenia
- 详细技术说明
- None
- *Abstract
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A method of diagnosing, assessing susceptibility, and/or treating schizophrenia involving the observation of regulator of G-protein signaling 4 (RGS4) levels in a subject. Embodiments of the present invention include increasing RGS4 expression levels in the cortex, either by chemical means or by genetic complementation (e.g. gene therapy). The present invention relates generally to the field of neurological and physiological dysfunctions associated with schizophrenia. The invention further relates to the identification, isolation, and cloning of genes which, when mutated or varied, are associated with schizophrenia. The present invention also relates to methods for diagnosing and detecting carriers of the genes and to diagnosis of schizophrenia. The present invention further relates to the construction of animal models of schizophrenia.
- *Principal Investigation
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Name: Pat Levitt, Chairman & Professor
Department: Med-Psychiatry
Name: Karoly Mirnics, Research Assistant Prof.
Department: Med-Psychiatry
- 国家/地区
- 美国
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