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Cylindrical probe for ex-situ nuclear magnetic resonance spectroscopy (Technion)

总结

This invention is concerned with a new type of ex-situ Nuclear Magnetic Resonance (NMR) probe with spectroscopic capability. NMR, and its descendant, Magnetic Resonance Imaging (MRI) are among the most powerful and versatile analytic and diagnostic methods in science. Current devices suffer from the need to employ large magnets that surround the examined sample/object. The large magnet, and the corresponding large RF coils are a major factor in the complexity and high cost of NMR and MRI systems. In addition in many cases the sample cannot be placed inside the bore of the magnet, or cannot be moved. The present invention describes a new type of ex-situ NMR probe, which through innovative design achieves mobile NMR/MRI capability. The achievable spectral resolution is in the order of ~0.5-1 ppm.The new ex-situ probe is designed by finite element software, which calculated the static and RF magnetic fields profiles. The novel aspects of the invention are the introduction of a new type of ex-situ probe that uses cylindrical symmetry to improve performance over existing designs. Improved performance is reflected by better SNR, better spectral resolution, larger volume of measurement and larger distance of signal acquisition away from the probe surface. The design novelties are:The new ex-situ probe is designed by finite element software, which calculated the static and RF magnetic fields profiles. The novel aspects of the invention are the introduction of a new type of ex-situ probe that uses cylindrical symmetry to improve performance over existing designs. Improved performance is reflected by better SNR, better spectral resolution, larger volume of measurement and larger distance of signal acquisition away from the probe surface. The design novelties are:

技术优势

The invention can be employed in the near future to a variety of applications where NMR measurements are required for samples located outside the magnet. For example, measurements during chemical reactions, quality inspection of chemicals and common commercial products (e.g. wine, medicine) stored in containers without opening them, and the measurements and characterization of rare art items. In the future this approach may find its use also in medical diagnostic applications.

ID号码

MED-0939

国家/地区

以色列