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Patient-specific 3D neurological simulation for Brain

总结
The company builds upon the discovery of the critical network parameters of the human brain, their influence to functional processes and their proper tweaking to rectify a malfunctioning or damaged network. Rather than making simplifying assumptions about topology, density and range of large-scale connectivity (anatomical realism), the company will invoke the Connectome, simultaneously integrating multiple modes of network activity. The company purposes to include an array of new and useful measures for the brain's organization thanks to extensive use of graph theory: segregation, integration, efficiency and influence of subnetworks, nodes and their edges. For the first time, the company will provide the same qualities and quantifications of common neuro‐imaging methods (EEG, MEG, fMRI) as a real brain, making it ideal for experimental validation and customization. Realizing that network nodes in actual human beings are far from homogenous, the company captures the functioning of the sub‐networks of the human brain through the novel concept of the space-time structure of the network couplings featuring means for quantifiable coupling matrices within and across regions.
该公司建立于人类大脑的关键神经网络参数的发现,及其对作用过程的影响和如何适当地调整它们来改正故障或损坏的神经网络。该公司将调用神经连接体, 同时整合多重模式的网络活动, 而不是仅对拓扑结构、密度、和大规模连接的范围(组织现实主义)进行简单的假设。该公司目的是要包含一批新的和有用的测量方法进行大脑的组织结构检测, 这些方法得益于图论的广泛应用:隔离,整合,效率和子网络的影响,节点和他们的边缘。 该公司第一次通过常见神经影像学方法(EEG、MEG 、fMRI)方法为真实的人脑提供了相同品质和量化检测,使它可理想的用于实验验证和定制化服务。意识到真实的人体内的网络节点情况大相径庭,该公司通过创新的时空结构的网络耦合特征方式在区域内外进行可量化的耦合矩阵, 来获得人类大脑子网络的功能。Clinical Applications: With a full function patient-specific 3D neurological simulation capacity, the company can predict impact of surgery, selected drugs, trauma, interventions and generate all brain metrics and can be applicable for use for all brain-related disease and injuries.
临床应用: 一个全功能的基于患者的三维神经模拟, 该公司可以预测手术的影响,药物的选择,创伤,干预措施和生成所有大脑指标, 可适用于所有的大脑相关的疾病和损伤
技术应用
其它
详细技术说明
Stage: $40M has been invested to date in this technology. They are seeking commercialization partners and additional funding opportunities.
阶段: 这项技术已得4千万加元投资。寻求商业合作伙伴和额外的资金机会
合作类型
技术售让
覆盖范围
生物技术/制药/医疗
商品和服务
生物技术工程

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