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Biodegradable and bioabsorbable biomaterials and keratin fibrous articles for medical applications

总结: The present invention relates to a process of making biodegradable and/or bioabsorbable biomaterials and keratin nonwoven fibrous articles by electrospinning fibers from a blend of biomaterials and keratin dissolved in organic solvents includes generating a high voltage electric field between oppositely charged biomaterials and keratin fluid in a syringe with a capillary tip and a metallic collection roller and causing a jet to flow to the roller as solvent evaporates and collecting fibrous membranes or scaffolds on the roller. Keratin increased the cell affinity of biomaterial scaffolds which have potential medical applications.

附加资料: Patent Number: US8242073B2
Application Number: US2008216717A
Inventor: Li, Yi | Li, Jiashen | Hu, Junyan | Li, Lin
Priority Date: 10 Jul 2008
Priority Number: US8242073B2
Application Date: 10 Jul 2008
Publication Date: 14 Aug 2012
IPC Current: C07K001400 | A61L001500
US Class: 5140212 | 514002 | 424445
Assignee Applicant: The Hong Kong Polytechnic University
Title: Biodegradable and bioabsorbable biomaterials and keratin fibrous articles for medical applications
Usefulness: Biodegradable and bioabsorbable biomaterials and keratin fibrous articles for medical applications
Summary: Method of making a biomaterial and keratin nonwoven fibrous article (claimed), e.g. polymeric membrane or scaffold for medical applications.
Novelty: Making a biomaterial and keratin nonwoven fibrous article by dissolving macromolecule material for electrospinning in solvent, delivering solution to electrode, applying voltage, moving collecting plate, and sputtering membrane with metal

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