Label-Free Optical Sensing And Characterization Of Biomolecules By D8 Or D10 Metal Complexes
- 总结
- The Present Invention Provides A Composition For Detecting And/Or Characterizing A Multiple-Charged Biomolecule Comprising A Charged D8 Or D10 Metal Complex, Wherein The Metal Complex Electrostatically Binds To The Multiple-Charged Biomolecule To Induce Aggregation And Self-Assembly Of The Metal Complex Through Metal . . . Metal Interactions, [Pi] . . . [Pi] Interactions, Or A Combination Of Both Interactions. The Present Invention Further Provides Assay Methods And Kits For Label-Free Optical Detection And/Or Characterization Of Biomolecules Carrying Multiple Charges, E.G., Single-Stranded Nucleic Acids, Polyaspartate, Polyglutamate, Using A Composition Comprising A Charged D8 Or D10 Metal Complex.
- 主要类别
- 生物医学
- 细分类别
- DNA /基因工程
- 申请号码
- US2007625109A
- 国家/地区
- 香港
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