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Methods For The Identification Of Inhibitors Of Asparagine Synthase As Antibiotics

总结

The Present Inventors Have Discovered That Asparagine Synthase Is Essential For Fungal Pathogenicity. Specifically, The Inhibition Of Asparagine Synthase Gene Expression In Fungi Results In No Signs Of Successful Infection Or Lesions. Thus, Asparagine Synthase Can Be Used As A Target For The Identification Of Antibiotics, Preferably Antifungals. Accordingly, The Present Invention Provides Methods For The Identification Of Compounds That Inhibit Asparagine Synthase Expression Or Activity. The Methods Of The Invention Are Useful For The Identification Of Antibiotics, Preferably Antifungals.

附加资料

Inventor: Blair, Loudon T. | Cornelius, Steven W. | Koehler, Steffen | Meagher, Kevin | Mizrahi, Victor
Priority Number: US6141125A
IPC Current: H04B0010077 | H04B001027
US Class: 398032 | 359110 | 385024 | 398001 | 398031 | 398083 | 359124 | 359119 | 359152
Assignee Applicant: CIENA Corporation,Linthicum
Title: Intra-node diagnostic signal
Usefulness: Intra-node diagnostic signal
Summary: For optical communication system.
Novelty: Communications network monitoring involves transmitting first service optical signal from first to second nodal component of first node, and transmitting second service optical signal from first to second

主要类别

信息和通信技术/电信

细分类别

电信

国家/地区

香港