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Method For Decreasing Blood Glucose And Improving Glucose Tolerance Using Angiopoietin-Like Protein 4

总结

Angiopoietin Like Protein 4 Is A Novel Circulating Protein Predominantly Expressed In Adipose Tissue And Liver. Several Recent Studies Demonstrated That Angiopoietin Like Protein 4 Is The Target Gene Of Peroxisome Proliferation Activators, The Agonists Of Which Are Widely Used As The Anti-Diabetic And Lipid-Lowering Drugs. The Invention Provides A Method For Decreasing Blood Glucose Or Improving Insulin Sensitivity In A Mammal In Need Thereof, Comprising Administering To The Patient An Amount Of Angiopoietin Like Protein-4 (Angptl4) Polypeptide Effective To Decrease Blood Glucose, To Improve Glucose Tolerance, Or To Increase Insulin Sensitivity.

附加资料

Patent Number: US20080019911A1
Application Number: US2006375297A
Inventor: Xu, Aimin | Lam, Karen, S.L.
Priority Date: 20 Apr 2005
Priority Number: US20080019911A1
Application Date: 14 Mar 2006
Publication Date: 24 Jan 2008
IPC Current: A61K004900 | A61K003816 | A61P000310 | C12Q000102 | G01N003368
US Class: 4240092 | 435029 | 436086 | 5140067 | 5140068 | 5140069 | 5140133 | 514789 | 514012
Title: Method for decreasing blood glucose and improving glucose tolerance using angiopoietin-like protein 4
Usefulness: Method for decreasing blood glucose and improving glucose tolerance using angiopoietin-like protein 4
Summary: The method is useful in decreasing blood glucose, improving glucose tolerance or increasing insulin sensitivity in a mammal or in treating diabetes or insulin resistance in an individual (claimed).
Novelty: Decreasing blood glucose, improving glucose tolerance or increasing insulin sensitivity for treating diabetes or insulin resistance in a mammal by administering angiopoietin like protein-4 (ANGPTL4) polypeptide

主要类别

诊断/治疗

细分类别

其他疾病

申请号码

US2006375297A

国家/地区

香港