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Therapeutic Inhibitor for EpsteinBarr Virus (EBV)-associated Cancers with Responsive Optical Imaging Function - Gold Medal

       
 
 
Summary
provides method of treating and imaging EBV-associated cancers.
Technology Benefits
Treating and imaging EBV-associated cancers
Technology Application
detection diagnosis
Detailed Technology Description
This invention provides a nucleus-permeable small-molecule inhibitor, L2P4 (where L2 is 4-(4-(Diethylamino)styryl)-N-carboxymethylpyridinium chloride and P4 is an amino acid sequence comprising CAhxYFMVFGGRrRK and they were coupled through amide bond) and synthesis thereof, which effectively targets the dimerization interface of EBNA1, a critical process for the growth of EBVs and the associated tumors. The present invention also provides method of treating and imaging EBV-associated cancers.
Type of Cooperation
Licensing
Publication Country/ Region
US
Application Date
24/04/2017 00:00:00
Application No.
15/495,971
Patent Information
A61K/51/00
Others
CN, TW, EP
Country/Region
Hong Kong

 

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